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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40810 | Rachelmycin | NSC298223,CC-1065 | |
Rachelmycin (CC-1065; NSC 298223) is a potent naturally antibiotic isolated from Streptomyces zelensis . Rachelmycin binds non-covalently and covalently (N-3 adenine adduct) in the minor groove of B-form DNA. Rachelmycin... | |||
T10701 | (+)-CBI-CDPI2 | Others | |
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. | |||
T10974 | DC41 | Others | |
DC41 is a derivative of DC1. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylating agents, used for targeted treatment of cancer. | |||
T10700 | (+)-CBI-CDPI1 | Others | |
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. It is a DNA alkylating agent and an antibody-drug conjugates (ADCs) toxin. | |||
T10973 | DC41SMe | Others | |
DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used fo... | |||
T10970 | DC1 | Others | |
DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer, is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. | |||
T68031 | Adolezesin | U 73975,Adozelesin ; U 73975,Adozelesin | |
https://pubmed.ncbi.nlm.nih.gov/1624543/ | |||
T10969 | DC1SMe | Others | |
DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 ... |